The product being tested is a salamol CFC-free Easi-Breathe inhaler Each actuation of the inhaler delivers Salbutamol Sulphate Ph Eur equivalent to Salbutamol 100 micrograms into the mouthpiece of the adapter. Salbutamol is a selective β2-adrenoceptor agonist. At therapeutic doses it acts on the β2-adrenoceptors of bronchial smooth muscle providing short acting (4-6 hour) bronchodilatation with a fast onset (within 5 minutes) in reversible airways obstruction. Salamol is indicated in the management of bronchial asthma, …showed first 75 words of 1725 total…

…showed last 75 words of 1725 total…respirable lungs. Therefore according to this MMAD value a majority of the particles are able to reach respirable regions. This was illustrated by the fact that very particles were present on the first three plates (0,1,2) References *<Tab/>www.medicines.org *<Tab/>Aulton, M.E., 2002. Pharmaceutics "The Science Of Dosage Form Design" Second Edition. Churchill Livingstone, pp.476-485. *<Tab/>Dr Paul Carter, 2003 lecture support